Version 5.4
Homo sapiens Protein: FITM1
Summary
InnateDB Protein IDBP-585938.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FITM1
Protein Name fat storage-inducing transmembrane protein 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000453741
InnateDB Gene IDBG-3545 (FITM1)
Protein Structure
UniProt Annotation
Function Plays an important role in lipid droplet accumulation. {ECO:0000269PubMed:18160536}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000269PubMed:18160536}; Multi-pass membrane protein {ECO:0000269PubMed:18160536}.
Disease Associations
Tissue Specificity Primarily expressed in heart and skeletal muscle. {ECO:0000269PubMed:18160536}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0010890 positive regulation of sequestering of triglyceride
GO:0034389 lipid particle organization
Cellular Component
GO:0005789 endoplasmic reticulum membrane
Protein Structure and Domains
PDB ID
InterPro IPR019388 Fat storage-inducing transmembrane protein
PFAM PF10261
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A5D6W6
PhosphoSite PhosphoSite-A5D6W6
TrEMBL
UniProt Splice Variant
Entrez Gene 161247
UniGene Hs.128060
RefSeq
HUGO HGNC:33714
OMIM 612028
CCDS
HPRD 17312
IMGT
EMBL BC042179 BC139911 CH471078
GenPept AAI39912 EAW66107

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca