Version 5.4
Homo sapiens Protein: DUOXA1
Summary
InnateDB Protein IDBP-586143.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DUOXA1
Protein Name dual oxidase maturation factor 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000453836
InnateDB Gene IDBG-10130 (DUOXA1)
Protein Structure
UniProt Annotation
Function May be required for the maturation and the transport from the endoplasmic reticulum to the plasma membrane of functional DUOX1. {ECO:0000305PubMed:16651268}.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Specifically expressed in thyroid gland. Also detected in esophagus. {ECO:0000269PubMed:16651268}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0015031 protein transport
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR018469 Dual oxidase maturation factor
PFAM PF10204
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q1HG43
PhosphoSite PhosphoSite-
TrEMBL H0YNR1
UniProt Splice Variant
Entrez Gene 90527
UniGene Hs.356664
RefSeq NP_001263196
HUGO HGNC:26507
OMIM 612771
CCDS CCDS61619
HPRD 14829
IMGT
EMBL AC091117 AK056896 BC020841 BC029819 CH471082 DQ489735 EU927395
GenPept AAH20841 AAH29819 ABF48257 ACH57454 BAB71304 EAW77290 EAW77292 EAW77293

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca