InnateDB Protein
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IDBP-586308.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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TGFBR3
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Protein Name
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transforming growth factor, beta receptor III
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Synonyms
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betaglycan; BGCAN;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000432638
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InnateDB Gene
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IDBG-100244 (TGFBR3)
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Protein Structure
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Function |
Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors.
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Subcellular Localization |
Secreted. Secreted, extracellular space. Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Note=Exists both as a membrane-bound form and as soluble form in serum and in the extracellular matrix.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated |
Total |
12
[view]
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Protein-Protein |
12
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
2 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001507
Zona pellucida domain
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PFAM |
PF00100
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PRINTS |
PR00023
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PIRSF |
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SMART |
SM00241
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TIGRFAMs |
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Modification |
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SwissProt |
Q03167
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PhosphoSite |
PhosphoSite-Q03167
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TrEMBL |
E9PAW7
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UniProt Splice Variant |
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Entrez Gene |
7049
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UniGene |
Hs.739252
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RefSeq |
NP_001182612
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HUGO |
HGNC:11774
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OMIM |
600742
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CCDS |
CCDS55614
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HPRD |
02846
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IMGT |
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EMBL |
AC099334
AC114486
AJ251961
AK291345
AL162263
AL390780
AL445992
AY796304
BC126116
BC136295
L07594
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GenPept |
AAA67061
AAI26117
AAI36296
AAV50003
BAF84034
CAB64374
CAI13392
CAI13393
CAI14570
CAI14571
CAI22636
CAI22637
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