Version 5.4
Homo sapiens Protein: TPK1
Summary
InnateDB Protein IDBP-587285.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TPK1
Protein Name thiamin pyrophosphokinase 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000438813
InnateDB Gene IDBG-46676 (TPK1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004788 thiamine diphosphokinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0030975 thiamine binding
Biological Process
GO:0009229 thiamine diphosphate biosynthetic process
GO:0016310 phosphorylation
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR007371 Thiamin pyrophosphokinase, catalytic domain
IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain
PFAM PF04263
PF04265
PRINTS
PIRSF
SMART SM00983
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q6ZQX6
UniProt Splice Variant
Entrez Gene 27010
UniGene Hs.660232
RefSeq
HUGO HGNC:17358
OMIM 606370
CCDS
HPRD 06967
IMGT
EMBL AC004534 AC004743 AC004833 AC004864 AC005677 AC074384 AK128661
GenPept BAC87556

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca