Homo sapiens Protein: BCORL1
Summary
InnateDB Protein IDBP-587400.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BCORL1
Protein Name BCL6 corepressor-like 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000437775
InnateDB Gene IDBG-85885 (BCORL1)
Protein Structure
UniProt Annotation
Function Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence- specific DNA-binding proteins such as BCL6. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. {ECO:0000269PubMed:17379597}.
Subcellular Localization Nucleus {ECO:0000269PubMed:17379597}.
Disease Associations
Tissue Specificity Detected in testis and prostate. Detected at lower levels in peripheral blood leukocytes and spleen. {ECO:0000269PubMed:17379597}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
Experimentally validated
Total 15 [view]
Protein-Protein 14 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0016568 chromatin modification
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
Protein Structure and Domains
PDB ID
InterPro IPR002110 Ankyrin repeat
IPR020683 Ankyrin repeat-containing domain
PFAM PF00023
PF13606
PF11929
PF12796
PRINTS PR01415
PIRSF
SMART SM00248
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5H9F3
PhosphoSite PhosphoSite-Q5H9F3
TrEMBL Q9HAM3
UniProt Splice Variant
Entrez Gene 63035
UniGene Hs.618004
RefSeq NP_068765
HUGO HGNC:25657
OMIM 300688
CCDS CCDS14616
HPRD 06517
IMGT
EMBL AK021424 AK074089 AK124676 AL034405 AL096777 AL136450 Z82208
GenPept BAB13821 BAB84915 BAC85922 CAB46626 CAI42768 CAI42769 CAI42770 CAI42884 CAI42885