Homo sapiens Protein: HOXD8
Summary
InnateDB Protein IDBP-588280.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HOXD8
Protein Name homeobox D8
Synonyms HOX4; HOX4E; HOX5.4;
Species Homo sapiens
Ensembl Protein ENSP00000437431
InnateDB Gene IDBG-75735 (HOXD8)
Protein Structure
UniProt Annotation
Function Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Subcellular Localization Nucleus.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007275 multicellular organismal development
GO:0008595 anterior/posterior axis specification, embryo
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001356 Homeobox domain
IPR009057 Homeodomain-like
IPR020479 Homeodomain, metazoa
PFAM PF00046
PRINTS PR00024
PIRSF
SMART SM00389
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P13378
PhosphoSite PhosphoSite-P13378
TrEMBL F8VSA3
UniProt Splice Variant
Entrez Gene 3234
UniGene Hs.301963
RefSeq
HUGO HGNC:5139
OMIM 142985
CCDS
HPRD 00868
IMGT
EMBL AC009336 AL520835 AY014303 AY014304 BC038709 BC090853 X15507
GenPept AAG42152 AAH38709 AAH90853 CAA33529