Version 5.4
Homo sapiens Protein: RRAS2
Summary
InnateDB Protein IDBP-588433.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RRAS2
Protein Name related RAS viral (r-ras) oncogene homolog 2
Synonyms TC21;
Species Homo sapiens
Ensembl Protein ENSP00000437547
InnateDB Gene IDBG-33051 (RRAS2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 27 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 27 [view]
Protein-Protein 25 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
Biological Process
GO:0001649 osteoblast differentiation
GO:0006184 GTP catabolic process
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0015031 protein transport
Cellular Component
GO:0005622 intracellular
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000795 Elongation factor, GTP-binding domain
IPR001806 Small GTPase superfamily
IPR003578 Small GTPase superfamily, Rho type
IPR003579 Small GTPase superfamily, Rab type
IPR005225 Small GTP-binding protein domain
IPR006689 Small GTPase superfamily, ARF/SAR type
IPR013684 Mitochondrial Rho-like
IPR020849 Small GTPase superfamily, Ras type
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00009
PF00071
PF00025
PF08477
PRINTS PR00315
PR00449
PR00328
PIRSF
SMART SM00174
SM00175
SM00173
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P62070
PhosphoSite PhosphoSite-P62070
TrEMBL E9PQ87
UniProt Splice Variant
Entrez Gene 22800
UniGene Hs.502004
RefSeq NP_001170785
HUGO HGNC:17271
OMIM 600098
CCDS CCDS53603
HPRD 02518
IMGT
EMBL AC011084 AF493924 AK300103 AK302033 AK313976 BC013106 CH471064 M31468
GenPept AAA36545 AAH13106 AAM12638 BAG36690 BAH13210 BAH13612 EAW68487

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca