InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RPTOR

Summary

InnateDB Protein

IDBP-588496.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RPTOR

Protein Name

regulatory associated protein of MTOR, complex 1

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000442479

InnateDB Gene

IDBG-71820 (RPTOR)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 127 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	127 [view]
Protein-Protein	127 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001030	RNA polymerase III type 1 promoter DNA binding
GO:0001031	RNA polymerase III type 2 promoter DNA binding
GO:0001032	RNA polymerase III type 3 promoter DNA binding
GO:0001156	TFIIIC-class transcription factor binding
GO:0005488	binding
GO:0005515	protein binding
GO:0019901	protein kinase binding
GO:0032403	protein complex binding
GO:0071889	14-3-3 protein binding

Biological Process

GO:0007050	cell cycle arrest
GO:0008286	insulin receptor signaling pathway
GO:0008361	regulation of cell size
GO:0016049	cell growth
GO:0031669	cellular response to nutrient levels
GO:0031929	TOR signaling
GO:0032008	positive regulation of TOR signaling
GO:0045945	positive regulation of transcription from RNA polymerase III promoter
GO:0071230	cellular response to amino acid stimulus
GO:0071902	positive regulation of protein serine/threonine kinase activity