InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PSMA4

Summary

InnateDB Protein

IDBP-588507.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PSMA4

Protein Name

proteasome (prosome, macropain) subunit, alpha type, 4

Synonyms

HC9; HsT17706; PSC9;

Species

Homo sapiens

Ensembl Protein

ENSP00000453323

InnateDB Gene

IDBG-24777 (PSMA4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 116 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	116 [view]
Protein-Protein	112 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	4 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004175	endopeptidase activity
GO:0004298	threonine-type endopeptidase activity

Biological Process

GO:0006511	ubiquitin-dependent protein catabolic process
GO:0051603	proteolysis involved in cellular protein catabolic process

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005839	proteasome core complex
GO:0019773	proteasome core complex, alpha-subunit complex

Protein Structure and Domains

PDB ID

InterPro

IPR000426 Proteasome alpha-subunit, N-terminal domain
IPR001353 Proteasome, subunit alpha/beta
IPR029055 Nucleophile aminohydrolases, N-terminal

PFAM

PF10584
PF00227

PRINTS

PIRSF

SMART

SM00948

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

H0YLS6

UniProt Splice Variant

Entrez Gene

5685

UniGene

Hs.718340

RefSeq

HUGO

HGNC:9533

OMIM

176846

CCDS

HPRD

10168

IMGT

EMBL

AC027228

GenPept