Homo sapiens Protein: ZNF468
Summary
InnateDB Protein IDBP-588550.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZNF468
Protein Name zinc finger protein 468
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000445669
InnateDB Gene IDBG-67151 (ZNF468)
Protein Structure
UniProt Annotation
Function May be involved in transcriptional regulation.
Subcellular Localization Nucleus {ECO:0000305}.
Disease Associations
Tissue Specificity Isoform 1 and isoform 2 are highly expressed in placenta, pancreas, and small intestine. Lower expression in colon, ovary, testis, prostate, thymus, spleen, kidney, and liver. No expression detected in heart and brain. {ECO:0000269PubMed:16144304}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001909 Krueppel-associated box
IPR007087 Zinc finger, C2H2
IPR015880 Zinc finger, C2H2-like
PFAM PF01352
PF00096
PRINTS
PIRSF
SMART SM00349
SM00355
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5VIY5
PhosphoSite PhosphoSite-Q5VIY5
TrEMBL
UniProt Splice Variant
Entrez Gene 90333
UniGene Hs.621021
RefSeq
HUGO HGNC:33105
OMIM
CCDS
HPRD 18344
IMGT
EMBL AC008813 AY442330 AY442331 CH471135 CR749381 CR936599
GenPept AAS01603 AAS01604 CAH18233 CAI56747 EAW72100