Version 5.4
Homo sapiens Protein: CD59
Summary
InnateDB Protein IDBP-588629.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CD59
Protein Name CD59 molecule, complement regulatory protein
Synonyms 16.3A5; 1F5; EJ16; EJ30; EL32; G344; HRF-20; HRF20; MAC-IP; MACIF; MEM43; MIC11; MIN1; MIN2; MIN3; MIRL; MSK21; p18-20;
Species Homo sapiens
Ensembl Protein ENSP00000437122
InnateDB Gene IDBG-38813 (CD59)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
Experimentally validated
Total 14 [view]
Protein-Protein 14 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0001971 negative regulation of activation of membrane attack complex
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001526 CD59 antigen
IPR016054 Ly-6 antigen / uPA receptor -like
PFAM PF00021
PRINTS
PIRSF
SMART SM00134
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E9PNW4
UniProt Splice Variant
Entrez Gene 966
UniGene Hs.731705
RefSeq
HUGO HGNC:1689
OMIM 107271
CCDS
HPRD 00117
IMGT
EMBL AL049629
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca