Version 5.4
Homo sapiens Protein: RBP2
Summary
InnateDB Protein IDBP-58882.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RBP2
Protein Name retinol binding protein 2, cellular
Synonyms CRABP-II; CRBP2; CRBPII; RBPC2;
Species Homo sapiens
Ensembl Protein ENSP00000232217
InnateDB Gene IDBG-58880 (RBP2)
Protein Structure
UniProt Annotation
Function Intracellular transport of retinol.
Subcellular Localization Cytoplasm.
Disease Associations
Tissue Specificity Higher expression in adult small intestine and to a much lesser extent in fetal kidney. {ECO:0000269PubMed:11274389}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0005501 retinoid binding
GO:0016918 retinal binding
GO:0019841 retinol binding
Biological Process
GO:0001523 retinoid metabolic process
GO:0006776 vitamin A metabolic process
GO:0006810 transport
GO:0007603 phototransduction, visible light
GO:0008544 epidermis development
Cellular Component
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR000463 Cytosolic fatty-acid binding
IPR000566 Lipocalin/cytosolic fatty-acid binding domain
IPR011038 Calycin-like
PFAM PF00061
PF08212
PRINTS PR00178
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P50120
PhosphoSite PhosphoSite-P50120
TrEMBL D6RGE6
UniProt Splice Variant
Entrez Gene 5948
UniGene Hs.655516
RefSeq NP_004155
HUGO HGNC:9920
OMIM 180280
CCDS CCDS3109
HPRD 07184
IMGT
EMBL AC097103 AK291978 BC069296 BC069361 BC069396 BC069424 BC069447 BC069513 BC069522 CH471052 U13831
GenPept AAC50162 AAH69296 AAH69361 AAH69396 AAH69424 AAH69447 AAH69513 AAH69522 BAF84667 EAW79036

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca