InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CLPB

Summary

InnateDB Protein

IDBP-588991.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CLPB

Protein Name

ClpB caseinolytic peptidase B homolog (E. coli)

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000441518

InnateDB Gene

IDBG-63385 (CLPB)

Protein Structure

UniProt Annotation

Function

May function as a regulatory ATPase and be related to secretion/protein trafficking process.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.

Experimentally validated
Total	15 [view]
Protein-Protein	14 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008134	transcription factor binding
GO:0016301	kinase activity
GO:0016887	ATPase activity
GO:0017111	nucleoside-triphosphatase activity

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0008152	metabolic process
GO:0034605	cellular response to heat

Cellular Component

GO:0005575

cellular_component

Protein Structure and Domains

PDB ID

InterPro

IPR001270 ClpA/B family
IPR002078 RNA polymerase sigma factor 54 interaction domain
IPR002110 Ankyrin repeat
IPR003593 AAA+ ATPase domain
IPR003959 ATPase, AAA-type, core
IPR010488 Zeta toxin domain
IPR011704 ATPase, dynein-related, AAA domain
IPR019489 Clp ATPase, C-terminal
IPR020683 Ankyrin repeat-containing domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM