Version 5.4
Homo sapiens Protein: GEN1
Summary
InnateDB Protein IDBP-589301.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GEN1
Protein Name Gen homolog 1, endonuclease (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000433180
InnateDB Gene IDBG-31446 (GEN1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004518 nuclease activity
Biological Process
GO:0006281 DNA repair
GO:0090305 nucleic acid phosphodiester bond hydrolysis
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR006085 XPG N-terminal
IPR029060 PIN domain-like
PFAM PF00752
PRINTS
PIRSF
SMART SM00485
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E9PM30
UniProt Splice Variant
Entrez Gene 348654
UniGene Hs.467793
RefSeq
HUGO HGNC:26881
OMIM 612449
CCDS
HPRD 08813
IMGT
EMBL AC093731 AC097377
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca