Version 5.4
Homo sapiens Protein: METAP2
Summary
InnateDB Protein IDBP-589403.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol METAP2
Protein Name methionyl aminopeptidase 2
Synonyms MAP2; MNPEP; p67; p67eIF2;
Species Homo sapiens
Ensembl Protein ENSP00000446052
InnateDB Gene IDBG-51682 (METAP2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 16 [view]
Protein-Protein 14 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004177 aminopeptidase activity
GO:0008235 metalloexopeptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
Protein Structure and Domains
PDB ID
InterPro IPR000994 Peptidase M24, structural domain
IPR001714 Peptidase M24, methionine aminopeptidase
PFAM PF00557
PRINTS PR00599
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G3V1U3
UniProt Splice Variant
Entrez Gene 10988
UniGene Hs.713984
RefSeq
HUGO HGNC:16672
OMIM 601870
CCDS
HPRD 03522
IMGT
EMBL AC018475 CH471054
GenPept EAW97539

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca