InnateDB Protein
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IDBP-589475.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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CYBASC3
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Protein Name
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cytochrome b, ascorbate dependent 3
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000437390
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InnateDB Gene
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IDBG-50096 (CYBASC3)
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Protein Structure
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Function |
Ferric-chelate reductase that reduces Fe(3+) to Fe(2+) before its transport from the endosome to the cytoplasm. Probably uses ascorbate as electron donor (By similarity). {ECO:0000250}.
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Subcellular Localization |
Late endosome membrane {ECO:0000250}; Multi- pass membrane protein {ECO:0000250}. Lysosome membrane {ECO:0000269PubMed:17897319}; Multi-pass membrane protein {ECO:0000269PubMed:17897319}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR004877
Cytochrome b561, eukaryote
IPR006593
Cytochrome b561/ferric reductase transmembrane
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PFAM |
PF03188
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PRINTS |
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PIRSF |
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SMART |
SM00665
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TIGRFAMs |
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Modification |
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SwissProt |
Q8NBI2
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PhosphoSite |
PhosphoSite-
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TrEMBL |
F5H684
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UniProt Splice Variant |
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Entrez Gene |
220002
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UniGene |
Hs.640349
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RefSeq |
XP_006718529
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HUGO |
HGNC:23014
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OMIM |
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CCDS |
CCDS8004
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HPRD |
11316
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IMGT |
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EMBL |
AK056751
AK075559
AK297084
AP003108
BC004391
BC014045
BC047710
CH471076
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GenPept |
AAH04391
AAH14045
AAH47710
BAC11698
BAG51804
BAG59601
EAW73941
EAW73942
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