InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: STIM1

Summary

InnateDB Protein

IDBP-590184.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

STIM1

Protein Name

stromal interaction molecule 1

Synonyms

D11S4896E; GOK; IMD10; STRMK; TAM; TAM1;

Species

Homo sapiens

Ensembl Protein

ENSP00000436208

InnateDB Gene

IDBG-24705 (STIM1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 27 experimentally validated interaction(s) in this database.

Experimentally validated
Total	27 [view]
Protein-Protein	26 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0042802	identical protein binding
GO:0051010	microtubule plus-end binding

Biological Process

GO:0005513	detection of calcium ion
GO:0007596	blood coagulation
GO:0032237	activation of store-operated calcium channel activity
GO:0045087	innate immune response (InnateDB)
GO:0051924	regulation of calcium ion transport

Cellular Component

GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0005874	microtubule
GO:0005887	integral component of plasma membrane
GO:0030176	integral component of endoplasmic reticulum membrane
GO:0032541	cortical endoplasmic reticulum

Protein Structure and Domains

PDB ID

InterPro

IPR001660 Sterile alpha motif domain
IPR011510 Sterile alpha motif, type 2
IPR013761 Sterile alpha motif/pointed domain
IPR021129 Sterile alpha motif, type 1

PFAM

PF07647
PF00536

PRINTS

PIRSF

SMART

SM00454

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q13586