Version 5.4
Homo sapiens Protein: ALDH4A1
Summary
InnateDB Protein IDBP-590579.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ALDH4A1
Protein Name aldehyde dehydrogenase 4 family, member A1
Synonyms ALDH4; P5CD; P5CDh;
Species Homo sapiens
Ensembl Protein ENSP00000446071
InnateDB Gene IDBG-92044 (ALDH4A1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003842 1-pyrroline-5-carboxylate dehydrogenase activity
GO:0004029 aldehyde dehydrogenase (NAD) activity
GO:0009055 electron carrier activity
GO:0016491 oxidoreductase activity
GO:0042802 identical protein binding
Biological Process
GO:0006560 proline metabolic process
GO:0006561 proline biosynthetic process
GO:0006562 proline catabolic process
GO:0008152 metabolic process
GO:0010133 proline catabolic process to glutamate
GO:0019470 4-hydroxyproline catabolic process
GO:0034641 cellular nitrogen compound metabolic process
GO:0044281 small molecule metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005759 mitochondrial matrix
Protein Structure and Domains
PDB ID
InterPro IPR015590 Aldehyde dehydrogenase domain
IPR016161 Aldehyde/histidinol dehydrogenase
PFAM PF00171
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P30038
PhosphoSite PhosphoSite-P30038
TrEMBL
UniProt Splice Variant
Entrez Gene 8659
UniGene Hs.77448
RefSeq
HUGO HGNC:406
OMIM 606811
CCDS
HPRD 06009
IMGT
EMBL AK222486 AK289972 AK294552 AL080251 AL954340 BC007581 BC023600 BX537160 CH471134 FJ462711 U24266 U24267
GenPept AAC50500 AAC50501 AAH07581 AAH23600 ACN89883 BAD96206 BAF82661 BAG57755 CAI23417 CAI39493 EAW94858

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca