Version 5.4
Homo sapiens Protein: OXGR1
Summary
InnateDB Protein IDBP-590706.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OXGR1
Protein Name oxoglutarate (alpha-ketoglutarate) receptor 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000438800
InnateDB Gene IDBG-43718 (OXGR1)
Protein Structure
UniProt Annotation
Function Receptor for alpha-ketoglutarate. Seems to act exclusively through a G(q)-mediated pathway (By similarity). {ECO:0000250}.
Subcellular Localization Cell membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity Detected in kidney and, to a lower extend, in placenta. Not detected in brain tissues including the frontal cortex, caudate putamen, thalamus, hypothalamus, hippocampus or pons.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
IPR017452 GPCR, rhodopsin-like, 7TM
PFAM PF00001
PRINTS PR00237
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96P68
PhosphoSite PhosphoSite-
TrEMBL F5H6U5
UniProt Splice Variant
Entrez Gene 27199
UniGene Hs.352218
RefSeq XP_005254102
HUGO HGNC:4531
OMIM 606922
CCDS CCDS9482
HPRD 06082
IMGT
EMBL AB065877 AB083598 AF370886 AF411109 AJ305372 AK122639 AK313684 AL356486 BC103881 BC103882 BC103883 CH471085 JQ308179
GenPept AAI03882 AAI03883 AAI03884 AAL26480 AAM76912 AFF59489 BAB89311 BAC06095 BAG36433 BAG53633 CAC83857 CAI16508 EAX08964

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca