InnateDB Protein
|
IDBP-591357.3
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
BEST2
|
Protein Name
|
bestrophin 2
|
Synonyms
|
|
Species
|
Homo sapiens
|
Ensembl Protein
|
ENSP00000448310
|
InnateDB Gene
|
IDBG-30930 (BEST2)
|
Protein Structure
|
|
Function |
Forms calcium-sensitive chloride channels. Permeable to bicarbonate. {ECO:0000269PubMed:11904445, ECO:0000269PubMed:12907679, ECO:0000269PubMed:18400985}.
|
Subcellular Localization |
Cell membrane; Multi-pass membrane protein.
|
Disease Associations |
|
Tissue Specificity |
Mainly confined to the retinal pigment epithelium and colon. {ECO:0000269PubMed:12032738}.
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
|
Molecular Function |
|
Biological Process |
|
Cellular Component |
|
PDB ID |
|
InterPro |
IPR021134
Bestrophin/UPF0187
|
PFAM |
PF01062
|
PRINTS |
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q8NFU1
|
PhosphoSite |
PhosphoSite-Q8NFU1
|
TrEMBL |
|
UniProt Splice Variant |
|
Entrez Gene |
54831
|
UniGene |
Hs.435611
|
RefSeq |
|
HUGO |
HGNC:17107
|
OMIM |
607335
|
CCDS |
CCDS42506
|
HPRD |
|
IMGT |
|
EMBL |
AF440756
AK000139
AY515705
|
GenPept |
AAM76995
AAR99655
BAA90970
|
|
|