InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: NLGN3

Summary

InnateDB Protein

IDBP-591494.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NLGN3

Protein Name

neuroligin 3

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000445298

InnateDB Gene

IDBG-75254 (NLGN3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004872	receptor activity
GO:0005515	protein binding
GO:0016787	hydrolase activity
GO:0042043	neurexin family protein binding
GO:0050839	cell adhesion molecule binding

Biological Process

GO:0002087	regulation of respiratory gaseous exchange by neurological system process
GO:0006898	receptor-mediated endocytosis
GO:0007158	neuron cell-cell adhesion
GO:0007416	synapse assembly
GO:0007612	learning
GO:0008152	metabolic process
GO:0030534	adult behavior
GO:0035176	social behavior
GO:0048675	axon extension
GO:0050804	regulation of synaptic transmission
GO:0050808	synapse organization
GO:0051965	positive regulation of synapse assembly
GO:0051968	positive regulation of synaptic transmission, glutamatergic
GO:0060024	rhythmic synaptic transmission
GO:0060080	regulation of inhibitory postsynaptic membrane potential
GO:0071625	vocalization behavior
GO:0097104	postsynaptic membrane assembly
GO:0097105	presynaptic membrane assembly
GO:2000463	positive regulation of excitatory postsynaptic membrane potential
GO:2000969	positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity

Cellular Component

GO:0005887	integral component of plasma membrane
GO:0009986	cell surface
GO:0030054	cell junction
GO:0030139	endocytic vesicle
GO:0045202	synapse
GO:0060076	excitatory synapse