InnateDB Protein
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IDBP-591509.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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SAA2
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Protein Name
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serum amyloid A2
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000437162
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InnateDB Gene
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IDBG-34632 (SAA2)
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Protein Structure
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Function |
Major acute phase reactant. Apolipoprotein of the HDL complex.
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Subcellular Localization |
Secreted.
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Disease Associations |
Note=Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA2 protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function. {ECO:0000269PubMed:1463770}.
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Tissue Specificity |
Expressed by the liver; secreted in plasma.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
2
[view]
|
Protein-Protein |
1
[view]
|
Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR000096
Serum amyloid A protein
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PFAM |
PF00277
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PRINTS |
PR00306
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PIRSF |
PIRSF002472
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SMART |
SM00197
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TIGRFAMs |
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Modification |
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SwissProt |
P0DJI9
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PhosphoSite |
PhosphoSite-P0DJI9
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
6289
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UniGene |
Hs.731376
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RefSeq |
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HUGO |
HGNC:10514
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OMIM |
104751
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CCDS |
CCDS7833
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HPRD |
00098
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IMGT |
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EMBL |
AC090099
AK307163
BC020795
CH471064
J03474
M23699
M23700
M26152
X51440
X51444
X51445
X56653
|
GenPept |
AAA64800
AAA64801
AAA85338
AAB59539
AAH20795
CAA35805
CAA35809
CAA35810
CAA39975
EAW68414
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