Version 5.4
Homo sapiens Protein: LMX1B
Summary
InnateDB Protein IDBP-591723.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LMX1B
Protein Name LIM homeobox transcription factor 1, beta
Synonyms LMX1.2; NPS1;
Species Homo sapiens
Ensembl Protein ENSP00000436930
InnateDB Gene IDBG-85430 (LMX1B)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0001701 in utero embryonic development
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007275 multicellular organismal development
GO:0009953 dorsal/ventral pattern formation
GO:0030182 neuron differentiation
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001356 Homeobox domain
IPR001781 Zinc finger, LIM-type
IPR009057 Homeodomain-like
PFAM PF00046
PF00412
PRINTS
PIRSF
SMART SM00389
SM00132
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O60663
PhosphoSite PhosphoSite-O60663
TrEMBL Q9UE66
UniProt Splice Variant
Entrez Gene 4010
UniGene Hs.129133
RefSeq NP_002307
HUGO HGNC:6654
OMIM 602575
CCDS CCDS6866
HPRD 03986
IMGT
EMBL AF057135 AF059572 AF059573 AF059574 AF059575 AL161731 AL161908 BC069601 BC112120 BC113491 CH471090 U77457
GenPept AAC13544 AAC27294 AAC39738 AAH69601 AAI12121 AAI13492 CAH70294 CAH70295 CAI40917 CAI40918 EAW87642

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca