InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: G2E3

Summary

InnateDB Protein

IDBP-591819.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

G2E3

Protein Name

G2/M-phase specific E3 ubiquitin protein ligase

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000451653

InnateDB Gene

IDBG-4249 (G2E3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004842	ubiquitin-protein transferase activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0016874	ligase activity

Biological Process

GO:0006915	apoptotic process
GO:0016567	protein ubiquitination

Cellular Component

GO:0005730	nucleolus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR000569 HECT
IPR001965 Zinc finger, PHD-type
IPR011011 Zinc finger, FYVE/PHD-type

PFAM

PF00632

PRINTS

PIRSF

SMART

SM00119
SM00249

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

G3V5B6

UniProt Splice Variant

Entrez Gene

55632

UniGene

Hs.605081

RefSeq

HUGO

HGNC:20338

OMIM

611299

CCDS

HPRD

13851

IMGT

EMBL

AB037754 AK000340 AK022867 AL117355 BC000973

GenPept

AAH00973 BAA91095 BAA92571 BAB14280