InnateDB Protein
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IDBP-591840.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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PTGR2
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Protein Name
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prostaglandin reductase 2
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000452280
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InnateDB Gene
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IDBG-11675 (PTGR2)
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Protein Structure
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Function |
Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto- PGE2-alpha with highest activity towards 15-keto-PGE2. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation (By similarity). {ECO:0000250}.
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Subcellular Localization |
Cytoplasm {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Widely expressed. {ECO:0000269PubMed:15004468}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR011032
GroES (chaperonin 10)-like
IPR013149
Alcohol dehydrogenase, C-terminal
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PFAM |
PF00107
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8N8N7
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PhosphoSite |
PhosphoSite-Q8N8N7
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TrEMBL |
V9HW32
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UniProt Splice Variant |
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Entrez Gene |
145482
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UniGene |
Hs.632344
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RefSeq |
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HUGO |
HGNC:20149
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OMIM |
608642
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CCDS |
CCDS9820
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HPRD |
09782
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IMGT |
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EMBL |
AC005520
AK096410
AY346133
AY424308
BC059364
BX641118
CH471061
FJ224334
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GenPept |
AAH59364
AAR05101
AAR82927
ACI46026
BAC04781
CAE46055
EAW81132
EAW81135
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