Homo sapiens Protein: HK3
Summary
InnateDB Protein IDBP-59206.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HK3
Protein Name hexokinase 3 (white cell)
Synonyms HKIII; HXK3;
Species Homo sapiens
Ensembl Protein ENSP00000292432
InnateDB Gene IDBG-59204 (HK3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004340 glucokinase activity
GO:0004396 hexokinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008865 fructokinase activity
GO:0016773 phosphotransferase activity, alcohol group as acceptor
GO:0019158 mannokinase activity
GO:0019899 enzyme binding
GO:0042562 hormone binding
Biological Process
GO:0001678 cellular glucose homeostasis
GO:0005975 carbohydrate metabolic process
GO:0006096 glycolytic process
GO:0008645 hexose transport
GO:0015758 glucose transport
GO:0019318 hexose metabolic process
GO:0044281 small molecule metabolic process
GO:0046835 carbohydrate phosphorylation
GO:0051156 glucose 6-phosphate metabolic process
GO:0055085 transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0043234 protein complex
Protein Structure and Domains
PDB ID
InterPro IPR001312 Hexokinase
IPR022672 Hexokinase, N-terminal
IPR022673 Hexokinase, C-terminal
PFAM PF00349
PF03727
PRINTS PR00475
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P52790
PhosphoSite PhosphoSite-P52790
TrEMBL A0A024R7R1
UniProt Splice Variant
Entrez Gene 3101
UniGene
RefSeq NP_002106
HUGO HGNC:4925
OMIM 142570
CCDS CCDS4407
HPRD 00806
IMGT
EMBL BC028129 CH471195 U42303 U51333
GenPept AAC50422 AAC50732 AAH28129 EAW85048 EAW85049