Version 5.4
Homo sapiens Protein: CLIC5
Summary
InnateDB Protein IDBP-592271.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CLIC5
Protein Name chloride intracellular channel 5
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000439195
InnateDB Gene IDBG-89803 (CLIC5)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005247 voltage-gated chloride channel activity
GO:0005515 protein binding
Biological Process
GO:0006810 transport
GO:0006821 chloride transport
GO:0007565 female pregnancy
GO:0034765 regulation of ion transmembrane transport
GO:0044070 regulation of anion transport
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0005794 Golgi apparatus
GO:0005815 microtubule organizing center
GO:0005938 cell cortex
GO:0015629 actin cytoskeleton
GO:0016020 membrane
GO:0034707 chloride channel complex
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR002946 Intracellular chloride channel
IPR010987 Glutathione S-transferase, C-terminal-like
IPR012336 Thioredoxin-like fold
PFAM PF13098
PF13192
PF13462
PF13905
PRINTS PR01263
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NZA1
PhosphoSite PhosphoSite-Q9NZA1
TrEMBL
UniProt Splice Variant
Entrez Gene 53405
UniGene Hs.629445
RefSeq NP_001242952
HUGO HGNC:13517
OMIM 607293
CCDS CCDS59022
HPRD 06292
IMGT
EMBL AF216941 AK075144 AK075163 AK097048 AL050336 AL355522 AL357057 AL591211 AY032602 BC035968 CH471081
GenPept AAF66928 AAH35968 AAK52083 BAC11432 BAC11444 BAG53413 CAI21030 CAI21031 EAX04286 EAX04287

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca