Homo sapiens Protein: GLYATL2 | |||||||
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Summary | |||||||
InnateDB Protein | IDBP-592291.3 | ||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
Gene Symbol | GLYATL2 | ||||||
Protein Name | glycine-N-acyltransferase-like 2 | ||||||
Synonyms | |||||||
Species | Homo sapiens | ||||||
Ensembl Protein | ENSP00000434277 | ||||||
InnateDB Gene | IDBG-47970 (GLYATL2) | ||||||
Protein Structure | |||||||
UniProt Annotation | |||||||
Function | Mitochondrial acyltransferase which transfers the acyl group to the N-terminus of glycine. Conjugates numerous substrates, such as arachidonoyl-CoA and saturated medium and long-chain acyl-CoAs ranging from chain-length C8:0-CoA to C18:0- CoA, to form a variety of N-acylglycines. Shows a preference for monounsaturated fatty acid oleoyl-CoA (C18:1-CoA) as an acyl donor. Does not exhibit any activity toward C22:6-CoA and chenodeoxycholoyl-CoA, nor toward serine or alanine. {ECO:0000269PubMed:20305126}. | ||||||
Subcellular Localization | Endoplasmic reticulum {ECO:0000269PubMed:20305126}. | ||||||
Disease Associations | |||||||
Tissue Specificity | Expressed at highest levels in salivary gland and trachea. Also detected in thyroid gland, spinal cord, prostate, lung and fetal brain. {ECO:0000269PubMed:20305126}. | ||||||
Comments | |||||||
Interactions | |||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||
PDB ID | |||||||
InterPro |
IPR013652
Glycine N-acyltransferase, C-terminal IPR013653 FR47-like IPR015938 Glycine N-acyltransferase, N-terminal IPR016181 Acyl-CoA N-acyltransferase |
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PFAM |
PF08444
PF08445 PF06021 |
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PRINTS | |||||||
PIRSF | |||||||
SMART | |||||||
TIGRFAMs | |||||||
Post-translational Modifications | |||||||
Modification | |||||||
Cross-References | |||||||
SwissProt | Q8WU03 | ||||||
PhosphoSite | PhosphoSite-Q8WU03 | ||||||
TrEMBL | A0A024R4Z5 | ||||||
UniProt Splice Variant | |||||||
Entrez Gene | 219970 | ||||||
UniGene | Hs.254271 | ||||||
RefSeq | |||||||
HUGO | HGNC:24178 | ||||||
OMIM | 614762 | ||||||
CCDS | CCDS41649 | ||||||
HPRD | 16568 | ||||||
IMGT | |||||||
EMBL | AB207211 AF426250 BC016789 BC021682 CH471076 | ||||||
GenPept | AAH16789 AAH21682 AAO73139 BAF63415 EAW73826 EAW73827 | ||||||