Version 5.4
Homo sapiens Protein: DLGAP1
Summary
InnateDB Protein IDBP-592659.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DLGAP1
Protein Name discs, large (Drosophila) homolog-associated protein 1
Synonyms DAP-1; DAP-1-ALPHA; DAP-1-BETA; DAP1; DLGAP1A; DLGAP1B; GKAP; hGKAP; SAPAP1;
Species Homo sapiens
Ensembl Protein ENSP00000437817
InnateDB Gene IDBG-498 (DLGAP1)
Protein Structure
UniProt Annotation
Function Part of the postsynaptic scaffold in neuronal cells.
Subcellular Localization Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000250}. Cell junction, synapse {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed in brain.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 27 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 27 [view]
Protein-Protein 27 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007267 cell-cell signaling
GO:0007268 synaptic transmission
Cellular Component
GO:0005575 cellular_component
GO:0030054 cell junction
GO:0045211 postsynaptic membrane
Protein Structure and Domains
PDB ID
InterPro IPR005026 Guanylate-kinase-associated protein
PFAM PF03359
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O14490
PhosphoSite PhosphoSite-O14490
TrEMBL
UniProt Splice Variant
Entrez Gene 9229
UniGene Hs.667661
RefSeq NP_001229691
HUGO HGNC:2905
OMIM 605445
CCDS CCDS56052
HPRD 09260
IMGT
EMBL AB000276 AB000277 AK294717 AK294747 AK299880 AK316099 AP002472 AP002478 AP005130 AP005204 AP005241 BC136453 BC136454 CH471113 U67988
GenPept AAC51119 AAI36454 AAI36455 BAA23257 BAA23258 BAH11858 BAH11868 BAH13160 BAH14470 EAX01654 EAX01658 EAX01659

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca