Homo sapiens Protein: ETS1
Summary
InnateDB Protein IDBP-592666.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ETS1
Protein Name v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
Synonyms ETS-1; EWSR2; p54;
Species Homo sapiens
Ensembl Protein ENSP00000441430
InnateDB Gene IDBG-75897 (ETS1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 77 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 77 [view]
Protein-Protein 68 [view]
Protein-DNA 8 [view]
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0006366 transcription from RNA polymerase II promoter
GO:0006955 immune response
GO:0008285 negative regulation of cell proliferation
GO:0010595 positive regulation of endothelial cell migration
GO:0030578 PML body organization
GO:0042981 regulation of apoptotic process
GO:0045087 innate immune response (InnateDB)
GO:0045648 positive regulation of erythrocyte differentiation
GO:0045765 regulation of angiogenesis
GO:0045786 negative regulation of cell cycle
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0046677 response to antibiotic
GO:0048870 cell motility
GO:0051272 positive regulation of cellular component movement
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0045171 intercellular bridge
Protein Structure and Domains
PDB ID
InterPro IPR000418 Ets domain
PFAM PF00178
PRINTS PR00454
PIRSF
SMART SM00413
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P14921
PhosphoSite PhosphoSite-P14921
TrEMBL
UniProt Splice Variant
Entrez Gene 2113
UniGene Hs.595460
RefSeq NP_001155894
HUGO HGNC:3488
OMIM 164720
CCDS CCDS53724
HPRD 01260
IMGT
EMBL AP001995 AP003397 AY943926 BT019452 BX640634 J04101 M11921 S67063 X14798 X65469
GenPept AAA52409 AAA52410 AAB28747 AAV38259 AAY19514 CAA32903 CAA32904 CAE45783