InnateDB Protein
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IDBP-593551.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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SLC22A9
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Protein Name
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solute carrier family 22 (organic anion transporter), member 9
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000440206
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InnateDB Gene
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IDBG-52408 (SLC22A9)
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Protein Structure
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Function |
Sodium-independent organic anion transporter which exhibits high specificity for sulfated conjugates of xenobiotics and steroid hormones. It is also specifically activated by 3 to 5 carbons-containing short-chain fatty acids/SCFAs, including propionate, butyrate and valerate. May operate the exchange of sulfated organic components against short-chain fatty acids/SCFAs at the sinusoidal membrane of hepatocytes. {ECO:0000269PubMed:17393504}.
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Subcellular Localization |
Basolateral cell membrane {ECO:0000269PubMed:17393504}; Multi-pass membrane protein {ECO:0000269PubMed:17393504}. Note=Enriched at the sinusoidal part of the plasma membrane.
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Disease Associations |
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Tissue Specificity |
Specifically expressed in liver by hepatocytes (at protein level). {ECO:0000269PubMed:11327718, ECO:0000269PubMed:17393504}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8IVM8
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
114571
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UniGene |
Hs.502772
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RefSeq |
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HUGO |
HGNC:16261
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OMIM |
607579
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CCDS |
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HPRD |
06982
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IMGT |
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EMBL |
AB062418
AF440402
AJ295270
AK074246
AP000484
AP001880
BC022379
BC126288
CH471076
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GenPept |
AAH22379
AAI26289
AAP97316
BAB83517
BAB85030
CAC82910
EAW74148
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