Version 5.4
Homo sapiens Protein: POLG
Summary
InnateDB Protein IDBP-593563.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol POLG
Protein Name polymerase (DNA directed), gamma
Synonyms MDP1; MIRAS; MTDPS4A; MTDPS4B; PEO; POLG1; POLGA; SANDO; SCAE;
Species Homo sapiens
Ensembl Protein ENSP00000431395
InnateDB Gene IDBG-29260 (POLG)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
Biological Process
GO:0006260 DNA replication
GO:0006261 DNA-dependent DNA replication
Cellular Component
GO:0005760 gamma DNA polymerase complex
Protein Structure and Domains
PDB ID
InterPro IPR001098 DNA-directed DNA polymerase, family A, palm domain
PFAM PF00476
PRINTS
PIRSF
SMART SM00482
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H0YCD2
UniProt Splice Variant
Entrez Gene 5428
UniGene Hs.706868
RefSeq
HUGO HGNC:9179
OMIM 174763
CCDS
HPRD 01438
IMGT
EMBL AC124068
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca