Version 5.4
Homo sapiens Protein: MEIS3
Summary
InnateDB Protein IDBP-594106.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MEIS3
Protein Name Meis homeobox 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000453307
InnateDB Gene IDBG-59528 (MEIS3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Nucleus {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0051897 positive regulation of protein kinase B signaling
GO:2001234 negative regulation of apoptotic signaling pathway
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001356 Homeobox domain
IPR008422 Homeobox KN domain
IPR009057 Homeodomain-like
PFAM PF00046
PF05920
PRINTS
PIRSF
SMART SM00389
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q99687
PhosphoSite PhosphoSite-Q99687
TrEMBL
UniProt Splice Variant
Entrez Gene 56917
UniGene Hs.741404
RefSeq NP_064545
HUGO HGNC:29537
OMIM
CCDS CCDS33064
HPRD 14386
IMGT
EMBL AK289950 AL359938 BC025404 BC069251 CH471126 CR749687 U68385
GenPept AAB19195 AAH25404 AAH69251 BAF82639 CAB95771 CAH18472 EAW57482

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca