Version 5.4
Homo sapiens Protein: BNIPL
Summary
InnateDB Protein IDBP-594196.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BNIPL
Protein Name BCL2/adenovirus E1B 19kD interacting protein like
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000435072
InnateDB Gene IDBG-102263 (BNIPL)
Protein Structure
UniProt Annotation
Function May be a bridge molecule between BCL2 and ARHGAP1/CDC42 in promoting cell death. {ECO:0000269PubMed:12901880}.
Subcellular Localization
Disease Associations
Tissue Specificity Isoform 2 is expressed in placenta and lung. {ECO:0000269PubMed:12681488}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
Experimentally validated
Total 21 [view]
Protein-Protein 20 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042802 identical protein binding
Biological Process
GO:0006915 apoptotic process
GO:0008285 negative regulation of cell proliferation
GO:0040009 regulation of growth rate
Cellular Component
GO:0005634 nucleus
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR022181 Bcl2-/adenovirus E1B 19kDa-interacting protein 2
PFAM PF12496
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q7Z465
PhosphoSite PhosphoSite-
TrEMBL F8W685
UniProt Splice Variant
Entrez Gene 149428
UniGene Hs.591473
RefSeq
HUGO HGNC:16976
OMIM 611275
CCDS
HPRD 16557
IMGT
EMBL AF193056 AL590133 AY033000 AY078983 AY078984 BC027868 BC074779 BC074780
GenPept AAG22484 AAH27868 AAH74779 AAH74780 AAK54348 AAL85483 AAL85484 CAI13344 CAI13347

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca