Version 5.4
Homo sapiens Protein: SUPT3H
Summary
InnateDB Protein IDBP-594541.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SUPT3H
Protein Name suppressor of Ty 3 homolog (S. cerevisiae)
Synonyms SPT3; SPT3L;
Species Homo sapiens
Ensembl Protein ENSP00000436411
InnateDB Gene IDBG-89638 (SUPT3H)
Protein Structure
UniProt Annotation
Function Probable transcriptional activator. {ECO:0000269PubMed:9787080}.
Subcellular Localization Nucleus {ECO:0000269PubMed:11564863, ECO:0000269PubMed:9726987}.
Disease Associations
Tissue Specificity Expressed in all tissues tested including pancreas, kidney, skeletal muscle, liver, lung, placenta, brain and heart.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 42 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 42 [view]
Protein-Protein 40 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003713 transcription coactivator activity
GO:0004402 histone acetyltransferase activity
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006325 chromatin organization
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
GO:0016578 histone deubiquitination
GO:0043966 histone H3 acetylation
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0030914 STAGA complex
GO:0033276 transcription factor TFTC complex
Protein Structure and Domains
PDB ID
InterPro IPR003195 Transcription initiation factor IID, 18kDa subunit
IPR009072 Histone-fold
PFAM PF02269
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O75486
PhosphoSite PhosphoSite-O75486
TrEMBL Q5U608
UniProt Splice Variant
Entrez Gene 8464
UniGene Hs.368325
RefSeq XP_005249508
HUGO HGNC:11466
OMIM 602947
CCDS CCDS34465
HPRD 04254
IMGT
EMBL AF064804 AF069734 AF073930 AK303838 AK313874 AL096865 AL138880 AL161905 AL360272 AL499610 BC035816 BC050384 CH471081
GenPept AAC36098 AAC39904 AAC70014 AAH35816 AAH50384 BAG36602 BAG64782 CAH70846 CAH70848 CAH73344 CAI14625 CAI14627 CAI15664 CAI15666 CAI19927 EAX04274 EAX04275 EAX04276

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca