Homo sapiens Protein: RIMBP2
Summary
InnateDB Protein IDBP-595139.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RIMBP2
Protein Name RIMS binding protein 2
Synonyms PPP1R133; RBP2; RIM-BP2;
Species Homo sapiens
Ensembl Protein ENSP00000439159
InnateDB Gene IDBG-64700 (RIMBP2)
Protein Structure
UniProt Annotation
Function Plays a role in the synaptic transmission as bifunctional linker that interacts simultaneously with RIMS1, RIMS2, CACNA1D and CACNA1B. {ECO:0000250}.
Subcellular Localization Cell membrane {ECO:0000250}. Cell junction, synapse {ECO:0000250}. Note=Synaptic plasma membrane. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0010923 negative regulation of phosphatase activity
Cellular Component
GO:0005886 plasma membrane
GO:0030054 cell junction
GO:0045202 synapse
Protein Structure and Domains
PDB ID
InterPro IPR001452 SH3 domain
IPR003961 Fibronectin, type III
IPR011511 Variant SH3 domain
PFAM PF00018
PF14604
PF00041
PF01108
PF07653
PRINTS PR00452
PIRSF
SMART SM00326
SM00060
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O15034
PhosphoSite PhosphoSite-O15034
TrEMBL
UniProt Splice Variant
Entrez Gene 23504
UniGene Hs.657441
RefSeq XP_006719790
HUGO HGNC:30339
OMIM 611602
CCDS
HPRD 17183
IMGT
EMBL AB002316 AC063926 BC007632 BX641152
GenPept AAH07632 BAA20776 CAE46066