Version 5.4
Homo sapiens Protein: PPP2R3C
Summary
InnateDB Protein IDBP-595343.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PPP2R3C
Protein Name protein phosphatase 2, regulatory subunit B'', gamma
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000450815
InnateDB Gene IDBG-4702 (PPP2R3C)
Protein Structure
UniProt Annotation
Function May regulate MCM3AP phosphorylation through phosphatase recruitment. May play a role in the activation-induced cell death of B-cells (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000269PubMed:15820313}. Cytoplasm {ECO:0000269PubMed:15820313}. Note=Excluded from the nucleoli. Localization is cell cycle-dependent. Localizes to the cytoplasm during cytokinesis.
Disease Associations
Tissue Specificity Ubiquitously expressed in brain and other tissues. {ECO:0000269PubMed:12167160, ECO:0000269PubMed:15820313}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 6 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
Biological Process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005813 centrosome
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q969Q6
PhosphoSite PhosphoSite-Q969Q6
TrEMBL
UniProt Splice Variant
Entrez Gene 55012
UniGene Hs.530712
RefSeq
HUGO HGNC:17485
OMIM 615902
CCDS
HPRD 12622
IMGT
EMBL AK000651 AK293717 AY157304 AY518535 AY518537 BC006823 BC010293 BC012563 BC063438 BX248043 CH471078
GenPept AAH06823 AAH10293 AAH12563 AAH63438 AAO17045 AAT44532 AAT44533 BAA91308 BAG57148 CAD62352 EAW65886 EAW65887 EAW65889 EAW65890

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca