InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CYB5RL

Summary

InnateDB Protein

IDBP-595490.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CYB5RL

Protein Name

cytochrome b5 reductase-like

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000434343

InnateDB Gene

IDBG-226752 (CYB5RL)

Protein Structure

UniProt Annotation

Function

NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction. {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H
GO:0016491	oxidoreductase activity

Biological Process

GO:0055114

oxidation-reduction process

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR001221 Phenol hydroxylase reductase
IPR001433 Oxidoreductase FAD/NAD(P)-binding
IPR001834 NADH:cytochrome b5 reductase (CBR)
IPR008333 Oxidoreductase, FAD-binding domain
IPR017938 Riboflavin synthase-like beta-barrel
IPR019180 Oxidoreductase-like, N-terminal

PFAM

PF00175
PF00970
PF09791

PRINTS

PR00410
PR00406

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q6IPT4