Version 5.4
Homo sapiens Protein: NDUFB11
Summary
InnateDB Protein IDBP-59559.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NDUFB11
Protein Name NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000367042
InnateDB Gene IDBG-59557 (NDUFB11)
Protein Structure
UniProt Annotation
Function Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular Localization Mitochondrion inner membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Ubiquitous.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
Experimentally validated
Total 19 [view]
Protein-Protein 19 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0022904 respiratory electron transport chain
GO:0044237 cellular metabolic process
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005743 mitochondrial inner membrane
GO:0005747 mitochondrial respiratory chain complex I
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR019329 NADH:ubiquinone oxidoreductase, ESSS subunit
PFAM PF10183
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NX14
PhosphoSite PhosphoSite-Q9NX14
TrEMBL
UniProt Splice Variant
Entrez Gene 54539
UniGene Hs.594599
RefSeq NP_001129470
HUGO HGNC:20372
OMIM 300403
CCDS CCDS48100
HPRD 02323
IMGT
EMBL AF044213 AF251063 AK000501 AL513366 AY359056 BC010665 BC107805 CR457239
GenPept AAH10665 AAI07806 AAK34953 AAL32064 AAQ89415 BAA91208 CAG33520 CAI41698 CAI41699

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca