InnateDB Protein
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IDBP-595621.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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DZIP1
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Protein Name
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DAZ interacting protein 1
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Synonyms
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DZIP; DZIPt1;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000431168
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InnateDB Gene
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IDBG-42834 (DZIP1)
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Protein Structure
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Function |
May participate in spermatogenesis via its interaction with DAZ. {ECO:0000269PubMed:15081113}.
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Subcellular Localization |
Nucleus {ECO:0000269PubMed:15081113}. Cytoplasm {ECO:0000269PubMed:15081113}. Note=In testis, it is predominantly nuclear, with some cytoplasmic localization in spermatogonia. Colocalizes with DAZ and DAZL in primordial germ cells.
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Disease Associations |
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Tissue Specificity |
Predominantly expressed in testis. Also expressed in fetal brain, adult oocytes and ovary. Expressed in undifferentiated ES cells. In testis, it is probably specifically expressed in germ cells. Expressed in mature germ cells and secondary spermatocytes, while it is weakly or not expressed in primary spermatocytes. {ECO:0000269PubMed:15081113}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
8
[view]
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Protein-Protein |
8
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR007087
Zinc finger, C2H2
IPR015880
Zinc finger, C2H2-like
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PFAM |
PF00096
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PRINTS |
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PIRSF |
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SMART |
SM00355
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TIGRFAMs |
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Modification |
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SwissProt |
Q86YF9
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PhosphoSite |
PhosphoSite-Q86YF9
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
22873
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UniGene |
Hs.656580
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RefSeq |
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HUGO |
HGNC:20908
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OMIM |
608671
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CCDS |
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HPRD |
16363
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IMGT |
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EMBL |
AB023213
AF272347
AF272348
AL049931
AL139376
BC041804
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GenPept |
AAH41804
AAL36978
AAL36979
BAA76840
CAB43211
CAH71600
CAH71601
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