InnateDB Protein
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IDBP-595768.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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CHID1
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Protein Name
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chitinase domain containing 1
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000435503
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InnateDB Gene
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IDBG-18558 (CHID1)
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Protein Structure
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Function |
Saccharide- and LPS-binding protein with possible roles in pathogen sensing and endotoxin neutralization. Ligand-binding specificity relates to the length of the oligosaccharides, with preference for chitotetraose (in vitro). {ECO:0000269PubMed:20724479}.
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Subcellular Localization |
Secreted {ECO:0000269PubMed:16357325}. Lysosome {ECO:0000269PubMed:16357325}.
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Disease Associations |
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Tissue Specificity |
Expressed in cells of monocytic, T, B and epithelial origin. {ECO:0000269PubMed:16357325, ECO:0000269PubMed:20724479}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
4
[view]
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Protein-Protein |
4
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001223
Glycoside hydrolase, family 18, catalytic domain
IPR011583
Chitinase II
IPR017853
Glycoside hydrolase, superfamily
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PFAM |
PF00704
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PRINTS |
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PIRSF |
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SMART |
SM00636
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TIGRFAMs |
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Modification |
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SwissProt |
Q9BWS9
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PhosphoSite |
PhosphoSite-Q9BWS9
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TrEMBL |
H0YDL6
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UniProt Splice Variant |
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Entrez Gene |
66005
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UniGene |
Hs.144468
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RefSeq |
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HUGO |
HGNC:28474
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OMIM |
615692
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CCDS |
CCDS44511
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HPRD |
14550
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IMGT |
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EMBL |
AF212229
AK027711
AK075413
AK124697
AP006623
AY037151
BC000001
BC013642
BC095409
BN000479
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GenPept |
AAH00001
AAH13642
AAH95409
AAK14915
AAK67632
BAB55316
BAC11603
BAG54072
CAF32458
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