InnateDB Protein
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IDBP-59593.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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C9orf24
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Protein Name
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chromosome 9 open reading frame 24
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000368428
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InnateDB Gene
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IDBG-59591 (C9orf24)
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Protein Structure
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Function |
May play a role in spermatogenesis (By similarity). May be involved in differentiation or function of ciliated cells. {ECO:0000250, ECO:0000269PubMed:15242845}.
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Subcellular Localization |
Cytoplasm, cytoskeleton {ECO:0000250}. Nucleus {ECO:0000269PubMed:15242845}. Cytoplasm {ECO:0000269PubMed:15242845}. Note=Localizes to the manchette in elongating spermatids (By similarity). Predominantly perinuclear in bronchial epithelial cells but also detected in the nucleus in some primary epithelial cells and in a number of cell lines. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Expressed in epithelial cells of nasal polyps and in intact epithelium of bronchial biopsies from subjects with and without asthma. Strong expression in columnar cells with little or no expression in basal epithelial cells along the basement membrane. Strongly expressed in ciliated epithelial cells with lower levels in goblet cells (at protein level). {ECO:0000269PubMed:15242845}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
1
[view]
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Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8NCR6
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PhosphoSite |
PhosphoSite-Q8NCR6
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
84688
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UniGene |
Hs.50334
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RefSeq |
NP_671697
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HUGO |
HGNC:19919
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OMIM |
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CCDS |
CCDS6555
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HPRD |
12949
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IMGT |
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EMBL |
AF367474
AK058087
AK094751
AL356494
BC022084
BC029484
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GenPept |
AAH22084
AAH29484
AAK53410
BAB71657
BAC04412
CAI15976
CAI15977
CAI15978
CAI15979
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