Version 5.4
Homo sapiens Protein: STARD10
Summary
InnateDB Protein IDBP-596168.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol STARD10
Protein Name StAR-related lipid transfer (START) domain containing 10
Synonyms NY-CO-28; PCTP2; SDCCAG28;
Species Homo sapiens
Ensembl Protein ENSP00000438792
InnateDB Gene IDBG-232906 (STARD10)
Protein Structure
UniProt Annotation
Function May play metabolic roles in sperm maturation or fertilization (By similarity). Phospholipid transfer protein that preferentially selects lipid species containing a palmitoyl or stearoyl chain on the sn-1 and an unsaturated fatty acyl chain (18:1 or 18:2) on the sn-2 position. Able to transfer phosphatidylcholine (PC) and phosphatidyetanolamline (PE) between membranes. {ECO:0000250, ECO:0000269PubMed:15911624}.
Subcellular Localization Cell projection, cilium, flagellum {ECO:0000250}. Cytoplasm {ECO:0000269PubMed:17561512}. Membrane {ECO:0000269PubMed:17561512}. Note=In testis was predominantly detected at the flagella of elongated spermatids, with a strong signal also found at the tail of epididymal sperm (By similarity). Mainly cytosolic. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 4 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008289 lipid binding
Biological Process
GO:0006869 lipid transport
Cellular Component
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0042995 cell projection
Protein Structure and Domains
PDB ID
InterPro IPR002913 START domain
PFAM PF01852
PRINTS
PIRSF
SMART SM00234
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Y365
PhosphoSite PhosphoSite-Q9Y365
TrEMBL F5H8G1
UniProt Splice Variant
Entrez Gene 10809
UniGene Hs.665881
RefSeq
HUGO HGNC:10666
OMIM
CCDS CCDS41688
HPRD 18116
IMGT
EMBL AF039696 AF151810 AP002381 AP003065 BC007919 BC014033 CH471076
GenPept AAC18045 AAD34047 AAH07919 AAH14033 EAW74867 EAW74868 EAW74872

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca