Version 5.4
Homo sapiens Protein: UBE4A
Summary
InnateDB Protein IDBP-596545.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UBE4A
Protein Name ubiquitination factor E4A
Synonyms E4; UBOX2; UFD2;
Species Homo sapiens
Ensembl Protein ENSP00000438918
InnateDB Gene IDBG-73670 (UBE4A)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 17 [view]
Protein-Protein 17 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0034450 ubiquitin-ubiquitin ligase activity
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0016567 protein ubiquitination
Cellular Component
GO:0000151 ubiquitin ligase complex
Protein Structure and Domains
PDB ID
InterPro IPR003613 U box domain
IPR019474 Ubiquitin conjugation factor E4, core
PFAM PF04564
PF10408
PRINTS
PIRSF
SMART SM00504
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL B7Z7P0
UniProt Splice Variant
Entrez Gene 9354
UniGene Hs.75275
RefSeq
HUGO HGNC:12499
OMIM 603753
CCDS
HPRD 06793
IMGT
EMBL AK302328 AP001267 AP001582
GenPept BAH13676

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca