Version 5.4
Homo sapiens Protein: MLH3
Summary
InnateDB Protein IDBP-596606.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MLH3
Protein Name mutL homolog 3 (E. coli)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000451130
InnateDB Gene IDBG-12716 (MLH3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005524 ATP binding
Biological Process
GO:0006298 mismatch repair
GO:0007131 reciprocal meiotic recombination
Cellular Component
GO:0032300 mismatch repair complex
Protein Structure and Domains
PDB ID
InterPro IPR001202 WW domain
IPR014790 MutL, C-terminal, dimerisation
PFAM PF00397
PF08676
PRINTS
PIRSF
SMART SM00456
SM00853
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H0YJA3
UniProt Splice Variant
Entrez Gene 27030
UniGene Hs.603265
RefSeq XP_006720180
HUGO HGNC:7128
OMIM 604395
CCDS
HPRD 05094
IMGT
EMBL AL049780
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca