InnateDB Protein
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IDBP-598.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ARHGAP28
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Protein Name
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Rho GTPase activating protein 28
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000313506
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InnateDB Gene
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IDBG-594 (ARHGAP28)
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Protein Structure
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Function |
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. {ECO:0000250}.
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
Expressed in testis. Expressed at moderate level in kidney and ovary, and weakly expressed in spleen and skeletal muscle. {ECO:0000269PubMed:10718198}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
1
[view]
|
Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
Accession |
GO Term |
GO:0005096
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GTPase activator activity
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Biological Process |
GO:0007165
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signal transduction
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GO:0007264
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small GTPase mediated signal transduction
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GO:0043547
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positive regulation of GTPase activity
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GO:0051056
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regulation of small GTPase mediated signal transduction
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Cellular Component |
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PDB ID |
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InterPro |
IPR000198
Rho GTPase-activating protein domain
IPR008936
Rho GTPase activation protein
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PFAM |
PF00620
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PRINTS |
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PIRSF |
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SMART |
SM00324
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TIGRFAMs |
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Modification |
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SwissProt |
Q9P2N2
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PhosphoSite |
PhosphoSite-Q9P2N2
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TrEMBL |
J3KTC0
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UniProt Splice Variant |
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Entrez Gene |
79822
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UniGene |
Hs.738832
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RefSeq |
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HUGO |
HGNC:25509
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OMIM |
610592
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CCDS |
CCDS32785
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HPRD |
10961
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IMGT |
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EMBL |
AB037735
AK001174
AP005205
AP005210
BC033668
BC065274
BX648684
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GenPept |
AAH33668
AAH65274
BAA91533
BAA92552
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