Homo sapiens Protein: FRMPD1
Summary
InnateDB Protein IDBP-598084.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FRMPD1
Protein Name FERM and PDZ domain containing 1
Synonyms FRMD2;
Species Homo sapiens
Ensembl Protein ENSP00000444411
InnateDB Gene IDBG-65896 (FRMPD1)
Protein Structure
UniProt Annotation
Function Stabilizes membrane-bound GPSM1, and thereby promotes its interaction with GNAI1. {ECO:0000269PubMed:18566450}.
Subcellular Localization Cytoplasm, cytosol {ECO:0000269PubMed:18566450}. Cell membrane {ECO:0000269PubMed:18566450}; Peripheral membrane protein {ECO:0000269PubMed:18566450}; Cytoplasmic side {ECO:0000269PubMed:18566450}. Note=Found both in the cytoplasm and associated with the cell membrane.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000299 FERM domain
IPR001478 PDZ domain
IPR018979 FERM, N-terminal
IPR019748 FERM central domain
IPR019749 Band 4.1 domain
IPR029071 Ubiquitin-related domain
PFAM PF00595
PF13180
PF09379
PF00373
PRINTS
PIRSF
SMART SM00228
SM00295
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5SYB0
PhosphoSite PhosphoSite-Q5SYB0
TrEMBL F5H0G3
UniProt Splice Variant
Entrez Gene 22844
UniGene Hs.604514
RefSeq
HUGO HGNC:29159
OMIM
CCDS CCDS6612
HPRD 17018
IMGT
EMBL AB023184 AL513165 AL591470 BC114965 BX648967 CH471071
GenPept AAI14966 BAA76811 CAI12951 CAI16156 CAI46019 EAW58270 EAW58271