InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: HOPX

Summary

InnateDB Protein

IDBP-598162.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HOPX

Protein Name

HOP homeobox

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000450527

InnateDB Gene

IDBG-20189 (HOPX)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	10 [view]
Protein-Protein	9 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0001829	trophectodermal cell differentiation
GO:0006351	transcription, DNA-templated
GO:0007507	heart development
GO:0008016	regulation of heart contraction
GO:0016575	histone deacetylation
GO:0043393	regulation of protein binding
GO:0043415	positive regulation of skeletal muscle tissue regeneration
GO:0045596	negative regulation of cell differentiation
GO:0048286	lung alveolus development
GO:0051155	positive regulation of striated muscle cell differentiation