Version 5.4
Homo sapiens Protein: MLL
Summary
InnateDB Protein IDBP-598191.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MLL
Protein Name myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)
Synonyms ALL-1; CXXC7; HRX; HTRX1; MLL; MLL/GAS7; MLL1; MLL1A; TET1-MLL; TRX1; WDSTS;
Species Homo sapiens
Ensembl Protein ENSP00000436700
InnateDB Gene IDBG-73725 (MLL)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 143 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 143 [view]
Protein-Protein 130 [view]
Protein-DNA 9 [view]
Protein-RNA 0
DNA-DNA 4 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0008270 zinc ion binding
Biological Process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR002857 Zinc finger, CXXC-type
PFAM PF02008
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H7C5W4
UniProt Splice Variant
Entrez Gene 4297
UniGene Hs.734849
RefSeq
HUGO HGNC:7132
OMIM 159555
CCDS
HPRD 01162
IMGT
EMBL AP000941 AP001267
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca