InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: MNAT1

Summary

InnateDB Protein

IDBP-598506.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MNAT1

Protein Name

menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis)

Synonyms

CAP35; MAT1; RNF66; TFB3;

Species

Homo sapiens

Ensembl Protein

ENSP00000446437

InnateDB Gene

IDBG-8368 (MNAT1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 67 experimentally validated interaction(s) in this database.

Experimentally validated
Total	67 [view]
Protein-Protein	66 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008094	DNA-dependent ATPase activity
GO:0008270	zinc ion binding
GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity
GO:0047485	protein N-terminus binding

Biological Process

GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000082	G1/S transition of mitotic cell cycle
GO:0000086	G2/M transition of mitotic cell cycle
GO:0000278	mitotic cell cycle
GO:0000718	nucleotide-excision repair, DNA damage removal
GO:0006200	ATP catabolic process
GO:0006281	DNA repair
GO:0006283	transcription-coupled nucleotide-excision repair
GO:0006289	nucleotide-excision repair
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0006360	transcription from RNA polymerase I promoter
GO:0006361	transcription initiation from RNA polymerase I promoter
GO:0006362	transcription elongation from RNA polymerase I promoter
GO:0006363	termination of RNA polymerase I transcription
GO:0006366	transcription from RNA polymerase II promoter
GO:0006367	transcription initiation from RNA polymerase II promoter
GO:0006368	transcription elongation from RNA polymerase II promoter
GO:0006370	7-methylguanosine mRNA capping
GO:0006461	protein complex assembly
GO:0006468	protein phosphorylation
GO:0007049	cell cycle
GO:0008283	cell proliferation
GO:0010467	gene expression
GO:0016032	viral process
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0050434	positive regulation of viral transcription

Cellular Component

GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005675	holo TFIIH complex
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR001841 Zinc finger, RING-type
IPR003903 Ubiquitin interacting motif
IPR004575 Cdk-activating kinase assembly factor MAT1/Tfb3
IPR015877 Cdk-activating kinase assembly factor MAT1, centre

PFAM

PF13639
PF14634
PF02809
PF06391

PRINTS

PIRSF

PIRSF003338

SMART

SM00184
SM00726

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt